The GIANTS' 2019 season was a rollercoaster.

The AFL Women's team couldn't capitalise on their success in 2018 and, in an expanded competition, won just two games. They saw some success, though, withAlyce Parker and Haneen Zreika (the first Muslim woman to play AFL both nominated for the NAB AFLW Rising Star Award. Delma Gisu became the first GIANT from the Torres Strait Islands to play for the club at AFL or AFLW level.

Rebecca Beeson was crowned the 2019 Gabrielle Trainor Medallist after a sensational season having transitioned from a forward into a midfielder. Inaugural squad members Emma Swanson and Maddy Collier departed during the trade window, while the GIANTS would welcome ruck Jess Allan during the same period.

The GIANTS fielded a team in the VFL Women's competition for the first time, playing five invitational games. The strong GIANTS team won four of their five matches while all but two of their draftees in the 2019 NAB AFL Women's draft played at least one match in the GIANTS VFLW side.

The GIANTS' AFL campaign got off to a flyer with the GIANTS thumping Essendon at the newly re-named GIANTS Stadium. The GIANTS won three of their first four games but were heartbroken when co-captain Callan Ward suffered a season ending knee injury during the club's first win over Geelong in Geelong.

Despite some big wins the GIANTS' 2019 season would see-saw in a similar fashion to 2018 with injuries to Matt de Boer, Brett Deledio and Lachie Whitfield taking their toll. The injuries would provide great opportunity for the GIANTS' younger players with the club debuting seven players during the season.

One of the highlights of the season came in the final round of the season. Needing at least six goals to tie for the Coleman Medal, Jeremy Cameron produced the performance of a lifetime against an embattled Gold Coast. 

Cameron would kick nine goals in the GIANTS resounding win to claim the 2019 Coleman Medal, becoming the first men's player to claim an individual award. Cameron would also earn his second All Australian honours, being named at centre half-forward.

The GIANTS entered the 2019 finals series as underdogs, despite finishing sixth and earning a home final. Coming up against an in-form Western Bulldogs, the GIANTS dismantled the Dogs at GIANTS Stadium winning the elimination final by 58 points.

They would face the Brisbane Lions in a semi-final at the Gabba in what was another classic final involving the GIANTS. Trailing in the dying minutes small forward Brent Daniels kicked a brilliant running goal to put the GIANTS in front. The GIANTS held on to win by three points and progress to a preliminary final.

After two wins that surprised many pundits in the AFL community, the GIANTS faced Collingwood in Preliminary Final at the MCG. After trailing by three points at half-time, the GIANTS broke the game open in the third quarter. A goal to Jeremy Cameron early in the final term ut them five goals clear of the Magpies but the game was far from over.

Collingwood came storming back and with seconds to play Collingwood sent the ball into the forward fifty, only for second-year defender Sam Taylor to spoil the ball and help the GIANTS over the line.

The GIANTS won by four points to make it through to their first AFL Grand Final. The feat made all the more impressive with the GIANTS missing Toby Greene through suspension and Lachie Whitfield due to appendicitis. 

Grand Final week would saw Whitfield and Greene return to the line-up as large crowds swarmed Tom Wills Oval and later the MCG to watch the GIANTS' Grand Final training sessions.

Thousands of GIANTS fans snapped up tickets for the Grand Final and made the trip to Melbourne for the Grand Final Parade. A march of over five thousand GIANTS fans starting at the steps of Victorian Parliament saw Melbourne awash with Orange and Charcoal on Grand Final Day.

Despite Jeremy Cameron kicking the first goal of the game, the GIANTS were humbled by favourites Richmond in the Grand Final. The GIANTS could manage just three goals in an 87 point loss to the Tigers in front of over 100,000 people at the MCG.

Tim Taranto claimed the 2019 Kevin Sheedy Medal as the GIANTS' Club Champion while the club farewelled Dawson Simpson, Brett Deledio and Dylan Buckley through retirement, and Jonathon Patton, Adam Tomlinson and Aiden Bonar in the trade period.

In late November GIANTS inaugural AFLW captain Amanda Farrugia announced her immediate retirement with Alicia Eva named as her replacement.